Alternative Electronic Theses and Dissertations (AETDs) are styled with the University of Tennessee Health Science Center (UTHSC) Alternative ETD Formatting Guidelines (an adaption of the University of Oklahoma Health Sciences Center thesis and dissertation guidelines (9-2-23)) and are stored in the UTHSC Digital Commons (DC) repository in standard PDF format. The AETD Guidelines do not require the different standard of formatting required for ETDs.

AETDs that are not embargoed can be downloaded and viewed using Adobe Acrobat Reader/Pro or other PDF-reading software. AETDs may also be viewed using a PDF viewer web browser plugin. Recent AETDs may be under embargo for a specified period; for these documents, click on an AETD title to access the metadata page that contains the Abstract. All manuscripts have copyrights, and the reuse of content must be requested and approved by the AETD author. To facilitate contacting the author, use their ORCID ID link when available. AETDs have been posted in the UTHSC Digital Commons AETD repository since May 2025. To review the public access statistics for AETDs, use the Digital Commons analytical dashboard.

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Theses/Dissertations from 2025

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Activation of the P2XR7 Channel by Non-Nucleotide Agonists, Rua’a Abdulhamid Al-Aqtash

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A Semi-Mechanistic Model of Immune Tolerance Induction to Support Preclinical Development of a Human Monoclonal Antibody, Paridhi Gupta

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Deciphering Genotype-Phenotype Connections: Leveraging Pangenomes and Comprehensive Genome Variation, Flavia Villani

Theses/Dissertations from 2024

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The Role of MicroRNA-152 in the Pathogenesis of Diabetic Cardiomyopathy, Joy Olaoluwa Gbadegoye

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Representation of Nouns and Verbs During Play Between Caregivers and Children with Developmental Language Disorder, Alaina Grissom

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The Role of Skeletal Muscle AMPK/mTORC1 Signaling in Disrupted Metabolism during Chemotherapy Treatment and Recovery, Jessica L. Halle

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Understanding the Mechanism of VERU-111 Resistance and Discovering Novel Mechanisms of Action of VERU-111, Damilola Daniel Ikechukwu Oluwalana

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Aging Skeletal Muscle: Influence of Obesity and Role of the Exercise Responsive Nuclear Receptor NOR-1, Hector G. Paez

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WNT5B as a Therapeutic Target for Osteosarcoma Stemness, Metastasis, and Chemoresistance, Rachel S. Perkins

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Circulating Exosomes Alter Skeletal Muscle Gene Expression to Impair Insulin Sensitivity in Type 2 Diabetes and Mediate Adaptive Response to Exercise in Healthy Mice, Christopher R. Pitzer

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Taste and Learning in the Gustatory Cortex, Martin Raymond

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Evaluation of Sphingolipid Biosynthetic Inhibitor L-Cycloserine to Prevent Retinal Degeneration, Faiza Tahia

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Postural Control in Adults with Age-Related Hearing Loss, Elizabeth Tobener

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Targeting TRPC3: A Promising Therapeutic Strategy for Alzheimer's Disease, Jiaxing Wang

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Biological Evaluation of Anti-Cancer Activities of Novel Small-Molecule Tubulin Polymerization Inhibitors in Prostate and Pancreatic Cancer, Rui Wang

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The Role of Epigenetic Aberrations in The Cold Tumor Phenotype And Inflammatory Signaling in High-Risk Neuroblastoma, Pamela Morgan Watson

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Targeting Multiple Aspects of Neuroinflammation for Epilepsy, Nelufar Yasmen

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Development of a Novel Drug Delivery Platform to Treat HIV-Associated Neurocognitive Disorder, Lina Zhou

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The Role of Scribble in Activating the Sonic Hedgehog (SHH) Pathway and Its Role in the Progression of SHH-Medulloblastoma, Jingwen Zhu