Utilization of Glucose and Acetone Bodies by Gastrointestinal Tract in Fasting Normal and Diabetic Dogs

Document Type

Article

Publication Date

1-1-1945

Publication Title

Journal of Nervous and Mental Disease

Volume

102

Issue

2

Abstract

In the normal dog fasted 3 or 5 days, the organs drained by the portal vein remove significant amounts of glucose and acetone bodies, but have no consistent effectupon the blood lactic acid. In the depancreatized dog, 3 to 7 days after the with-drawal of food and insulin, these organs continue to remove statistically significant quantities of glucose and increase their removal of acetone bodies. Under these conditions they add lactic acid to the blood. If the glucose removed by the gastrointestinal tract of the depancreatized dog and not returned to the blood as lactate is oxidized, it will account for approximately 876 of the animal's resting metabolism. © 1946, SAGE Publications. All rights reserved.

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