Seroflocculating Steroids. VIII. Side Chain Reduction of Deoxycholic, 12α-Hydroxy-3-cholenic and 3α-Hydroxy-ll-cholenic Acids

Document Type

Article

Publication Date

1-1-1959

Publication Title

Journal of the American Chemical Society

Volume

81

Issue

11

Abstract

Methyl deoxycholate, methyl 12α-hydroxy-3-cholenate and methyl 3α-hydroxy-11-cholenate were reduced to the corresponding C-24 hydroxy compounds. The latter were selectively deoxylated at C-24 to give 3α, 12α-cholanediol, 3-cholen-12α-ol and 11-cholen-3α-ol, respectively. Some ester and chloro derivatives are active seroflocculants. © 1959, American Chemical Society. All rights reserved.

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