The origin of bile lecithin and the use of bile to determine plasma lecithin turnover rates

Document Type

Article

Publication Date

1-1-1958

Publication Title

Archives of Biochemistry and Biophysics

Volume

73

Issue

1

Abstract

Lecithin was extracted from hepatic bile of dogs injected with inorganic phosphate P32. The purified chloroform-methanol extract was found to contain all the phosphatide phosphorus and to be free of P32 contaminants. Comparison of liver, plasma, and bile phosphatide specific activities demonstrated that bile contains only lecithin, which is produced by the liver from the same precursor as is plasma lecithin. The collection of plasma and bile lecithin from chronic bile fistula dogs injected with P32 furnished a method for calculating the turnover rate of plasma lecithin. © 1958.

Share

COinS