The metabolism of magnesium and calcium by the rat
Document Type
Article
Publication Date
1-1-1959
Publication Title
Archives of Biochemistry and Biophysics
Volume
84
Issue
2
Abstract
1. 1. The metabolism of Mg28 has been compared to that of Ca45 when both were present in equimolar amounts and in the form of the chloride. Oral doses were contrasted to those given via intraperitoneal injection, and the effects of age were investigated. 2. 2. Magnesium was more readily absorbed than calcium and was excreted into the urine and feces in greater amounts than calcium. Few differences due to age were uncovered. 3. 3. The maximum uptake of radioactivity by bone occurred at 1 hr. for magnesium and at 16 hr. for calcium; more calcium was accumulated than magnesium. The soft tissues showed more magnesium than calcium. The discrimination factors at the various sites of selection were calculated from the data. 4. 4. When the proportions of stable calcium and magnesium in the dose were varied it was found that the inclusion of magnesium increased the uptake of Ca45 by bone beyond that expected, while raising the calcium and lowering the magnesium at first improved the Mg28 uptake by bone and then reduced it below the expected value. © 1959.
Recommended Citation
Lengemann, F.
(1959).
The metabolism of magnesium and calcium by the rat.
Archives of Biochemistry and Biophysics,
84(2).
http://doi.org/10.1016/0003-9861(59)90592-2
Retrieved from: https://dc.uthsc.edu/fac_pubs/391