Comparative Metabolism of Sr89 and Ca45 by Bone Grown in vitro

Document Type

Article

Publication Date

1-1-1957

Publication Title

Proceedings of the Society for Experimental Biology and Medicine

Volume

94

Issue

1

Abstract

An in vitro culturing technic was used in comparing metabolism of calcium-45 and strontium-89 in bone. The results of a large number of determinations indicated: a) that at 2 hrs bone contained 1.08 times as much strontium-89 as calcium-45; b) when exposed to constant levels of Sr89 and Ca45, the Observed Ratiobone-medium equilibrated at 0.83 within 7 days; c) strontium-89 was released from bone at a ratio of about 1.2 times that of calcium-45; d) addition of carrier strontium markedly inhibited the long term deposition of calcium in bone but the discriminatory mechanisms were unaltered. © 1956, Sage Publications. All rights reserved.

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