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Theses/Dissertations from 2023

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Physiologically-Based Pharmacokinetic (PBPK) Modeling for the Preclinical Development of Spectinamide Antibiotics, Keyur R. Parmar

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PKPD-Model Based Preclinical Characterization of the Activity of Spectinamide 1599 Against Mycobacterial Subpopulations. and the Identification of Potential Partners for Combination Therapy, Zaid Hanif Temrikar

Theses/Dissertations from 2021

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Combating HIV-1 by Targeting Drug Efflux Transporters on the Macrophage Reservoir, Ying Mu

Theses/Dissertations from 2020

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A Novel Elvitegravir Nanoformulation for Drug Delivery Across the Blood-Brain Barrier to Suppress HIV-1 in Macrophages and Microglia, Yuqing Gong

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Tobacco/HIV-1-Induced Myeloid Cell-Derived Extracellular Vesicles in HIV-1 Pathogenesis, Sanjana Haque

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Model-Based Dose-Exposure-Response Assessment for Lead and Backup Spectinamide in a Mouse Model of Tuberculosis, Santosh Janardan Wagh

Theses/Dissertations from 2018

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Somatic Mutation Detection in Leukemia-Derived Circulating DNA: Utility in Monitoring Clonal Dynamics and Disease Response in Pediatric Acute Lymphoblastic Leukemia, Sarah Hisham Abdelaziz Youssef

Theses/Dissertations from 2017

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Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation in the Development of Spectinamides, a Novel Class of Anti-Tuberculosis Agents, Chetan Rathi

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The Development of Methods to Account for Physiologic Dynamic Changes and Their Effects on the Pharmacokinetics of Therapeutic Monoclonal Antibodies and other Therapeutics, Josiah Thomas Ryman

Theses/Dissertations from 2016

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Discoveries of Targets and Novel Agents for the Treatment of Ischemic Retinopathy and Neovascular Disease, Jordan Javad Toutounchian