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Theses/Dissertations from 2020

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Development and Characterization of Selective CB2R Inverse Agonists as a Novel Anti-Inflammatory Therapy for Neuroinflammation – Mechanisms of Action in Murine and Human Microglia Models Provide Valuable Insights into Their Therapeutic Potential, Sahar Saleh Alghamdi

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Integrated Multimodal Genomic Analyses Reveal Novel Mechanisms of Glucocorticoid Resistance in Acute Lymphoblastic Leukemia, Robert J. Autry

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Unraveling Molecular Mechanisms Underlying the Development of Unconventional T Cells, Daniel Eduardo Bastardo Blanco

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Novel Paclitaxel Nanoparticles for Enhanced Therapeutic Effects in Breast Cancer, Pallabita Chowdhury

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A Dynamic Ankle Orthosis for Alleviating Mechanical Foot and Ankle Pain, Preserving Joint Motion, and Restoring Patient Function, Chloe Ly Chung

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Vestibular Evoked Myogenic Potentials and Postural Control in Adults with Age-Related Hearing Loss, Steven Michael Doettl

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A Novel Elvitegravir Nanoformulation for Drug Delivery Across the Blood-Brain Barrier to Suppress HIV-1 in Macrophages and Microglia, Yuqing Gong

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Tobacco/HIV-1-Induced Myeloid Cell-Derived Extracellular Vesicles in HIV-1 Pathogenesis, Sanjana Haque

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Design, Development and Evaluation of Dual Drug Nanomedicine for Non-Small Cell Lung Cancer, Elham Hatami

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Forecasting the Essential Chemotherapy Needed for Treatment of Children with Acute Lymphoblastic Leukemia in Low- and Middle-Income Countries, Brian T. Lewis

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MUC13 Modulated Nanomechanical and Biophysical Responses in Pancreatic Cancer Cells, Andrew E. Massey

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The Discovery and Development of Thienopyrimidines as Inhibitors of Helicobacter pylori, Alex Kagabo Mugengana

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Characterization of Novel CB2 Agonist SMM-295 and Its Effects in Ischemia/Reperfusion Injury, Jeffrey D. Pressly

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Development of Novel Therapeutic Strategies for Pancreatic Cancer Treatment, Saini Setua

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Arid1a Haploinsufficiency Initiates Neural Crest Transformation in a Mouse Model of Mycn-driven Neuroblastoma, Kirby A. Wallace

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Biochemical and Structural Characterization of the Atg8/LC3 Lipidation Pathway, Yumei Zheng

Theses/Dissertations from 2019

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An Update on Pharmaceutical Strategies for Oral Delivery of Therapeutic Peptides and Proteins, Nirnoy Dan

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Reverse Zoonosis of Pandemic A(H1N1)pdm09 Influenza Viruses at the Swine/Human Interface, Daniel Gene Darnell

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Roles of γδ T Cells in Influenza Infections and Methods for TCR Expression and Characterization, Xizhi Guo

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Cellular Corrosion of CoCrMo Total Knee Implants: Understanding Underlying Mechanisms Through Retrieval Analysis and Simulated Inflammatory Conditions, Griffin Heise

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Investigation of Cell-Type-Specific Effects and Synergistic Interactions Between Genes in Duplication 15q Syndrome, Kevin A. Hope

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Validation Testing of a Synthetic Spine and Upgraded Protocol for a Biomechanical Evaluation of a Lumbar Spinal Orthosis, Daniel Hoyer

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Regulation of CYP3A5 in Pancreatic Ductal Adenocarcinoma, Jessica D. Hoyer

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Investigation of Narrow Spectrum Targets in Antibacterial Drug Discovery, Jesse Jones

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The Role of Secretory Phospholipase A2 Group IIA in Obesity and Metabolism, Michael S. Kuefner