Seroflocculating Steroids. IV.¹ Unsaturated Bile Acid Esters²

Authors

Frederic C. Chang, University of Tennessee Health Science Center
Jane Ransom Gray, University of Tennessee Health Science Center
Douglas H. Sprunt, University of Tennessee Health Science Center
Aaron Feldstein, University of Massachusetts Chan Medical School
George S. McCaleb, University of Arkansas

Document Type

Article

Publication Date

5-5-1957

Publication Title

Journal of the American Chemical Society

Volume

79

Issue

9

Abstract

For study of their seroflocculating activity, methyl and ethyl 3,11-choladienate, methyl 3,9(11)-choladienate, methyl and ethyl 3-cholenate, methyl and ethyl 12α-hydroxy-3-cholenate were prepared by elimination of suitably constituted 3α-tosylates. Each elimination reaction appears to give a single (or highly predominant) oleflnic product. The assignment of the Δ3-structure to these compounds is based on the identity of our methyl cholenate with the product prepared previously by Fieser and Ettore and proved by them to be methyl 3-cholenate. © 1957, American Chemical Society. All rights reserved.

Recommended Citation

Chang, F., Gray, J., Sprunt, D., Feldstein, A., & McCaleb, G. (1957). Seroflocculating Steroids. IV.¹ Unsaturated Bile Acid Esters². Journal of the American Chemical Society, 79(9). http://doi.org/10.1021/ja01566a039
Retrieved from: https://dc.uthsc.edu/fac_pubs/193