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Theses/Dissertations from 2024

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Loss of the SAC Components SldA Kinase or SldB or in vitro Adaptation to Triazole Produces Aneuploidy Associated with Triazole Heteroresistance in Aspergillus fumigatus, Ashley Nywening

Theses/Dissertations from 2023

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Understanding the Host Cellular Response to Astrovirus Infection, Theresa Mary Taggart Bub

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T Cell Responsiveness Through the Ages: Functional Diversity of Age-Dependent Antiviral Responses, Brandi L. Clark

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Investigating Potential Quantitative Trait Loci for Susceptibility to Experimental Autoimmune Encephalomyelitis in the BXD Family of Mice, Margaret Caroline Danehy

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Investigation of Clinically Relevant Fluconazole Resistance Mechanisms in the Fungal Pathogen Candida parapsilosis, Laura Anne Doorley

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The Role of TCR Engagement Strength in Antitumor CD8 T Cell Exhaustion, Xin Lan

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Exogenous Mitochondrial Transfer and IL-6: Modulating Adipocyte Metabolism in Obesity-associated Dysregulation, Soumi Mazumdar

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Matrix Gene Splicing and Emergence of Highly Pathogenic Avian Influenza, Christopher Patton

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Impacts of Habitat, Resource Addition, and Predator Exclusion on Rodent Community Structure and Hantaviruses in the Neotropics, Briana Spruill-Harrell

Theses/Dissertations from 2022

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Methods Development in Inflammatory Bowel Disease, Andrew B. Steimke

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A Cloning-Free Recyclable System for CRISPR-Cas9 Mediated Mutant and Reversion Construction in Candida albicans Clinical Isolates, Amanda K. Vogel

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Identification of Therapeutic Targets for Th17 Cell-Mediated Diseases, Jin Wang

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Cellular Dynamics and Disease Outcome of Type 3 Streptococcus pneumoniae Clinical Isolates Differ Between Strains, Taylor Rae Plunkett White

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Characterizing T Cell Features of Atypical Lymphocytes for the Optimization of Adoptive Immunotherapies, Taylor L. Wilson

Theses/Dissertations from 2021

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Characterizing and Overcoming Resistance to Aminomethylspectinomycins in Gram-negative Bacteria, Nisha Das

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Environmental and Genetic Factors Affecting Bone Diseases and Phenotypes in Mouse Models, Wei Dong

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Examination of Antiviral Resistance in Venezuelan Equine Encephalitis Virus, Jasper Lee

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Delineating the Upc2A Regulon in Candida glabrata, Yu Li

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The Heme-Regulated Inhibitor Pathway Modulates Susceptibility of Poor Prognosis B-Lineage Acute Leukemia to BH3-Mimetics, Kaitlyn Hill Smith

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Advancing RNA Virus Discovery and Biology with Whole Genome Sequencing, Mariah Katherine Taylor

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Identification of Effectors of Synergistic Lethality in Candida albicans-Staphylococcus aureus Polymicrobial Intra-abdominal Infection, Olivia Adele Todd

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Ecology of Hantaviruses in Rodent Reservoirs and Their Early Innate Immune Responses in Human Model Systems, Evan Peter Williams

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Genomic Characterization of Sickle Cell Mouse Models for Therapeutic Genome Editing Applications, Kaitly Jensen Woodard

Theses/Dissertations from 2020

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Unraveling Molecular Mechanisms Underlying the Development of Unconventional T Cells, Daniel Eduardo Bastardo Blanco

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Validation and Application of a Novel Target-Based Whole-Cell Screen to Identify Antifungal Compounds, Christian Alexander DeJarnette

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Understanding Human Astrovirus from Pathogenesis to Treatment, Virginia Hargest

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Dissecting Drivers of Basal Immunity and Acute Responses to Viral Infection, Aisha Nadia Hegab Souquette

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Attenuation of Interferon Responses in the Obese Host and Ramifications for Influenza Virus Evolution, Rebekah Reed Honce

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Biochemical and Structural Characterization of the Atg8/LC3 Lipidation Pathway, Yumei Zheng

Theses/Dissertations from 2019

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Reverse Zoonosis of Pandemic A(H1N1)pdm09 Influenza Viruses at the Swine/Human Interface, Daniel Gene Darnell

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Roles of γδ T Cells in Influenza Infections and Methods for TCR Expression and Characterization, Xizhi Guo

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Transcriptional Regulation of NLRC4 Inflammasome by IRF8, Ein Lee

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Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus, Jeffrey Michael Rybak

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Antibiotic Drug Discovery Targeting Bacterial Metabolism, Miranda J. Wallace

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Investigation of Riluzole’s Synaptic Protection Mechanism Through HSF1-BDNF Axis, Yi Zhang

Theses/Dissertations from 2018

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Characterization of the Hepatotoxicity of Rifampicin and Isoniazid, Christopher T. Brewer

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The Role of BiP Co-chaperone SIL1 in Marinesco-Sjögren Syndrome Pathogenesis, Viraj Paresh Ichhaporia

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The Role of Exosomal Transport of Viral Agents in Persistent HIV Pathogenesis, Benjamin J. Patters

Theses/Dissertations from 2017

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Role of Dendritic Cells in Pathology of Respiratory Syncytial Virus Infection in Neonates, Bishwas Shrestha

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Genome-scale Precision Proteomics Identifies Cancer Signaling Networks and Therapeutic Vulnerabilities, Hong Wang

Theses/Dissertations from 2016

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Interaction Between Two E3 ligases, NEDD8ylated Cullin and HHARI, Kheewoong Baek

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Assessment of the Zoonotic Potential of a Novel Bovine Influenza Virus, Laura Evelyn Eckard

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Dissecting the Novel Roles of TRIM56 in Antiviral Innate Immunity, Baoming Liu

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Endosomal Trafficking as a Determinant of Antifungal Tolerance in the Pathogenic Fungus Candida albicans, Arturo Luis Luna

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Pten Signaling in Regulatory T Cells and Inflammatory Disease, Sharad Krishna Shrestha

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Understanding Structural And Functional Mechanisms of Emi1 Inhibition of the Anaphase Promoting Complex, Edmond Randall Watson

Theses/Dissertations from 2015

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Development of Oral Vaccines Against Lyme Disease, Rita Raquel dos Anjos de Carvalho e Melo

Theses/Dissertations from 2014

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Strengths and Weaknesses of Hybrid TPR Technology for Obtaining Structural and Mechanistic Insights into TPR Proteins, Shanshan Yu

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Autoimmune Susceptibility Imposed by Public TCRβ Chains, Yunqian Zhao

Theses/Dissertations from 2013

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A Novel Mechanism of Enhanced Susceptibility to Bacterial Pneumonia in Influenza-infected Hosts, Hazem Elsayed Ghoneim