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Theses/Dissertations from 2013

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Regulation of Secretory Phospholipase A2 by Thyroid Hormone, Pragya Sharma

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Attenuation of Parenteral NutritionAssociated Liver Disease by Omega-3 Long-Chain Polyunsaturated Fatty Acids, Emma Monique Tillman

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The Protumorigenic Role of Caspase-8 in Neuroblastoma, Devin Drew Twitchell

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Signal Transduction and Transcriptional Regulation Pathways Essential for Azole Resistance in Candida albicans, Erin M. Vasicek

Theses/Dissertations from 2012

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The Molecular Basis of Fitness and Transmissibility of Neuraminidase Inhibitor Resistant Influenza A Viruses, Susu Duan

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Acetaldehyde and Epithelial Junctions: Role of Pp2A and Occludin Phosphorylation, Mitzi Dunagan

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CNS Penetration of Tyrosine Kinase Inhibitors in Mouse Models, Mohamed Elmeliegy

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Neocortical Layer 4 to Layer 2/3 Sensory Information Processing Investigated with Digital-Light-Projection Neuronal Photostimulation, Jason Paul Jerome

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Hematopoietic Stem Cell Threshold Sensing Controls Regulatory Pathways Facilitating Clinically Relevant Ex Vivo Expansion for Stem Cell Transplantation, Andrew D. Lasiter

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Inhibition of Breast Cancer Angiogenesis and Metastasis ay Targeting Hypoxia-Inducible Factor-1α, Chikezie O. Madu

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Mrp4 Is a Crucial Regulator of Testosterone Biosynthesis, Jessica Ann Morgan

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Anti-apoptotic MCL-1 Localizes to the Mitochondrial Matrix and Couples Mitochondrial Fusion to Respiration, Rhonda Perciavalle

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Contribution of the Unfolded Protein Response to VEGF Expression, Ethel Rose Pereira

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The Role of the YXXΦ Motif in CD82 Trafficking and Function, Mekel Marie Richardson

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Phenotypic And Electrophysiologic Characterization of a Mouse Model of Fragile X Syndrome, Snigdha Roy

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The Role of BiP Nucleotide Exchange Factor Sil1 in Immunoglobulin Biosynthesis, Tyler Sanford

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Discovery of Dihydroartemisinin and Dasatinib Drug Combination to Cure Pooroutcome BCR-ABL+ Acute Lymphoblastic Leukemia, Harpreet Singh

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Metabotropic Glutamate Receptor 5 in the Medial Prefrontal Cortex: Role in Cocaine Sensitization and Addiction, Kristin Marie Timmer

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Beta-2-Adrenergic Receptor Regulates Insulin Signaling to Reduce Cell Death in Müller Cells, Robert Jason Walker

Theses/Dissertations from 2011

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The Biochemical Pathway Leading to Lpa Generation Upon Blood Coagulation, Alyssa Lynn Jefferson Bolen

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Autoimmune Consequences of Histone Deimination during Neutrophil Activation, Nishant Dwivedi

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Impact of Adjuvants on the Antibody Responses to Pre-pandemic H5N1 Influenza Vaccines, Ali Hassan Ellebedy

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Insights into p53-Dependent Apoptotic Signaling and Cell Fate vis-a-vis Functional Cooperation among BCL-xL, Cytoplasmic p53, and PUMA, John C. Fisher

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A Behavioral and Anatomical Analysis of Conditioned Taste Aversion in C57BL/6J and DBA/2J Mice, April Rebecca Glatt

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The Treatment of Breast Cancer Tumor Growth and Metastasis With an Anti-MMP9 DNAzyme, Miranda A. Hallett

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Role of Protein Kinase C Zeta (PKCζ) in Regulation of Epithelial Tight Junctions, Suneet Kumar Jain

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Characterization of the Key Mouse Cochlear Developmental Genes for Auditory Hair Cell Regeneration, Zhiyong Liu

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Testing Whether MRP4 (a cAMP Efflux Pump) and the Beta 2 Andrenergic Receptor (an Upstream Regulator of cAMP Signaling Pathways, Praveen Kumar Potukuchi

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The Effects of PTEN Deletion on Cell Size and Plasticity in the Hippocampus, Margaret Sperow

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Systemic AAV-Mediated Gene Therapy Using Epo-R76E to Protect Retinal Ganglion Cells from Optic Nerve Injury and Disease, Timothy A. Sullivan

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Novel Insights into Ubiquitin-like Protein E1-E2 Interactions, Asad Taherbhoy

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Characterization of the Mechanism of PPARγ-Mediated Neointima Formation in Rodents, Ryoko Tsukahara

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Compound 49b: A Novel Beta-Adrenergic Receptor Agonist in the Treatment of Diabetic Retinopathy, Kimberly Williams-Guy

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Pten Function in Postnatal Brain Development and Tumorigenesis, Guo Zhu

Theses/Dissertations from 2010

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Role of Extracellular Signal-Regulated Kinase (ERK) in Regulation of Intestinal Epithelial Tight Junctions, Sudhir Aggarwal

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Characterizing Purkinje Cell Responses and Cerebellar Influence on Fluid Licking in the Mouse, Jeri Lonece Bryant

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Interactions of Francisella Tularensis With Components of the Host Fibrinolytic System, Shawn Russell Clinton

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NS1 of H5N1 Interacts with SAP-97 in a PDZ-dependent Manner to Disrupt Epithelial Barrier Integrity, Veronica Garcia Conoley

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Tetrahydroisoquinoline Neurotoxins in Parkinson Disease, Michael G. DeCuypere

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H5N1 Influenza Virus Induces a Parkinsonian Pathology, Haeman Jang

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The mGluR2/3 Agonist LY397268 Improves Morphometric and Behavioral Outcomes in R6/2 Huntington's Disease Mice, Dennis Craig Lafferty

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D2R Dopamine Receptor Mediates Changes in Dual Specificity Phosphatase Expression in a Small Cell Lung Cancer Cell Line, Scott Lemar Lattimer

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T-cell Receptor CDR3 Sequence but Not Recognition Characteristics Distinguish Autoreactive Effector and Foxp3+ Regulatory T-cells, Xin Liu

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Mitochondrial Regulation of Arterial Contractility, Damodaran Narayanan

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The Use of Preclinical Models to Improve the Treatment of Retinoblastoma, Katie Marie Nemeth

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The Effect of L-Proline on Two Recombinant AMPA Glutamate Receptors, Adetutu Abiose Oyelami

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The Role of Pkd1 in Mouse Inner Ear Hair Cells, Katherine Ann Steigelman

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Glycan Shielding of the Influenza Virus Hemagglutinin Elicits Evasion of the Adaptive Immune Response and T-Cell-Driven Pathology, Keith C. Wanzeck

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CD151 Reinforces Vascular Stability by Balancing Endothelial Cell Adhesion and Cytoskeletal Tension, Feng Zhang

Theses/Dissertations from 2009

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Regulation of Pyruvate Dehydrogenase Kinase 4 by Thyroid Hormone / Role of Peroxisome Proliferator Activated Receptor Gamma Coactivator-1 alpha and Ccaat Enhancer Binding Protein, Ramy Naguib Attia

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Structural and Kinetics Studies of the Enzyme Dihydropteroate Synthase and the Implications for Antibiotic Resistance, Katherine A. Ayers

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Contribution of Organic Cation Transporter 2 (OCT2) to Cisplatin-Induced Nephrotoxicity, Kelly K. Filipski

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Identification of the Downstream Effector Genes Involved in HOXB4-Induced Expansion of Hematopoietic Progenitor Cells, Jie Jiang

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Studying the Specificity of hPXR Antagonists Using a Panel of Cell-based Assays, Fang Lei

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Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia, Christopher B. Miller

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Physical and Functional Coupling of CFTR and PDE3A, Himabindu Penmatsa

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Pandemic Potential of Reassortant Swine Influenza A Viruses, Christy Brockwell Staats

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Insights into BTB-Cul3 Ubiquitin Ligases from the Structures of SPOP-Substrate Complexes, Min Zhuang

Theses/Dissertations from 2008

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Regulation of the Human Parainfluenza Virus (hPIV3) Fusion Protein, Amanda Ruth Chapman

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The Role of FGF Signaling in Retinal Development, Abbie A. Hartge

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Interaction of Bacteriophage Mu Middle Transcription Activator Protein Mor with Promoter DNA, Kartik Iyer

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Studies of Entry, Reverse Transcription, and Regulation of Splicing in Retroviruses, Timothy A. Sullivan

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Manipulation of the Moloney Murine Leukemia Virus Envelope Protein in an Effort to Develop Directly and Indirectly Targeted Retroviral Vectors for Use in Human Gene Therapy, Geneva M. Vasser

Theses/Dissertations from 2007

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The Cystic Fibrosis Transmembrane Conductance Regulator: Regulation by HSP-90, Kevin Marrs