Theses/Dissertations from 2017
Role of Dendritic Cells in Pathology of Respiratory Syncytial Virus Infection in Neonates, Bishwas Shrestha
Biophysical and Biochemical Screening Approaches for Antimicrobial Drug Discovery Targeting S. aureus ClpP, Aman Preet Singh
Revealing a Non-canonical Role of Anti-apoptotic MCL-1 in Early Embryonic Development, Xue Yang
Theses/Dissertations from 2016
Interaction Between Two E3 ligases, NEDD8ylated Cullin and HHARI, Kheewoong Baek
Investigating the Regulation and Function of the NR4A Nuclear Receptors in Cancer, Jordan A. Beard
The Nucleolar Protein Nucleophosmin Undergoes Liquid-Liquid Phase Separation with Arginine-Rich Nucleolar Proteins through Weak, Multivalent Electrostatic Interactions, Jaclyn Alicia Cika
Novel Oncogenic Drivers in Pediatric Gliomagenesis, Alexander K. Diaz
Antibodies to Heterogenous Nuclear Ribonucleoprotein A1 Penetrate Neurons Leading to Multiple Downstream Effects Resulting in Neurodegeneration, Joshua Nathan Douglas
Assessment of the Zoonotic Potential of a Novel Bovine Influenza Virus, Laura Evelyn Eckard
The Roles of Nuclear Receptor NR4A1 in Cancer Cell Proliferation and Skeletal Muscle Differentiation, Alexa Farmer
The Role of Drak2 in T Cell Function and Autoimmunity, Tarsha L. Harris
Regulation of IRF-3-Dependent Innate Immune Signaling Pathway by the PLpro Domain of Non-Structural Protein 3 (NSP3) of Severe Acute Respiratory Syndrome (SARS) Coronavirus, Sandra Nicole Lester
Dissecting the Novel Roles of TRIM56 in Antiviral Innate Immunity, Baoming Liu
Endosomal Trafficking as a Determinant of Antifungal Tolerance in the Pathogenic Fungus Candida albicans, Arturo Luis Luna
Role of Occludin in the Regulation of Epithelial Tight Junctions, Bhargavi Manda
Neuroanatomical Maps and Taste Reactivity to Sweet, Umami, and Bitter Taste in the PBN of C57BL/6J Mice, Jennifer Marie Saputra
Pten Signaling in Regulatory T Cells and Inflammatory Disease, Sharad Krishna Shrestha
Evaluating the Therapeutic Effect of an Hsp90 Inhibitor in Mouse Models of Alzheimer’s Disease, Bin Wang
Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain, Bo Wang
Understanding Structural And Functional Mechanisms of Emi1 Inhibition of the Anaphase Promoting Complex, Edmond Randall Watson
Environmental Signaling through the Target of Rapamycin Complex 1 (TORC1) and the Regulation of Epigenetic Mechanisms, Jason J. Workman
Repeated Zolpidem Treatment Effects on Sedative Tolerance, Withdrawal, mRNA Levels, and Protein Expression, Brittany T. Wright
Theses/Dissertations from 2015
Genetic Control of Survival and Weight Loss during Pneumonic Burkholderia pseudomallei (Bp) Infection, Felicia D. Emery
Integration of ATM, ATR, and DNA-PKcs Signaling Maintains Genome Integrity During Neurogenesis, Vanessa D. Enriquez-Rios
Reprogramming to Pluripotency Using Small Molecule Compounds, Brittany E. Greenberg
Molecular Mechanisms Underlying Alcohol-Induced Cerebral Artery Smooth Muscle BK Channel Inhibition and Eventual Cerebral Vasoconstriction, Guruprasad Kuntamallappanavar
Adverse Effects of Asparaginase in Pediatric Patients with Acute Lymphoblastic Leukemia, Chengcheng Liu
Development of Oral Vaccines Against Lyme Disease, Rita Raquel dos Anjos de Carvalho e Melo
Functional Analysis of Genomic Variation and Impact on Molecular and Higher Order Phenotypes, Ashutosh Kumar Pandey
Effects of Cocaine Sensitization on Drug Self-Administration, Mesocorticolimbic SAPAP Levels, and Prefrontal Ionotropic Glutamate Receptors, Kyle Christopher Summers
Structural-based Investigation of FAK and P130Cas in Focal Adhesion, Chi Zhang
Theses/Dissertations from 2014
Preclinical Evaluation of a Novel Polysaccharide Hydrogel for Local Chemotherapy Delivery to Solid Tumors, Elizabeth Diana Barker
Adenosine Production Is Essential for Closing the Critical Period of Cortical Plasticity, Rachel A. Chassan
The Mi-2 Homolog Mit1 Actively Positions Nucleosomes Within Heterochromatin to Suppress Transcription, Kevin M. Creamer
Molecular Characterization of Glioblastoma Cancer Stem Cells, Jo Meagan Garner
Functional and Genetic Analysis of Choroid Plexus Development in Zebrafish, Hannah Elizabeth Henson
Group IV Cytosolic Phospholipase A2α Is Critical for the Development of Angiotensin II-Induced Hypertension and Associated Pathogenesis, Nayaab Shehbaz Khan
Effect of Nedd4 Haploinsufficiency on Insulin Sensitivity, Adiposity and Neuronal Behaviors, Jingjing Li
Persistant GATA2 Expression Promotes Self-Renewal of Myeloid Progenitors and Blocks Lymphoid Differentiation., Satish Kumar Nandakumar
Novel Insights into the Role of the Smoothened Cysteine Rich Domain in Hedgehog Signalling, Rajashree Rana
Characterization of Cre Mouse Models to Target CNS Barriers for Generating Conditional Knockouts of ABC Transporters, Rachel L. Scheib
MRP4-Dependent Regulation of Fibroblast Migration, Chandrima Sinha
Genetic and Chemical Dissection of BloodBrain Barrier Development in Zebrafish, Robyn Anne Umans
The Role of MCL-1 in the Heart: Gateway from Life to Death, Xi Wang
Strengths and Weaknesses of Hybrid TPR Technology for Obtaining Structural and Mechanistic Insights into TPR Proteins, Shanshan Yu
Autoimmune Susceptibility Imposed by Public TCRβ Chains, Yunqian Zhao
Theses/Dissertations from 2013
Toll-like Receptors 2 and 9 Are Important for Innate Immune Cell Activation and Recruitment in Hypersensitivity Pneumonitis, Kelly J. Andrews
Macromolecular Complexes of Cystic Fibrosis Transmembrane Conductance Regulator Alter Fluid Transport in inflammatory Bowel Disorders, Kavisha Arora
Adenylyl Cyclase 2 Selectively Regulates IL-6 Expression in Human Bronchial Smooth Muscle Cells, Amy Sue Bogard
Development and Characterization of a Recombinant Vesicular Stomatitis Virus (rVSV) for the Treatment of Glioblastoma, Erika A. Dillard
Virologic Factors Contributing to the Genetic Diversification of Influenza Viruses Circulating in North American Swine, Thomas Paul Fabrizio II
ERG11-Mediated Azole Resistance in Candida albicans, Stephanie Ann Flowers
Functional Study of Hemogen Knockout Mouse Model, Peng Gao
A Novel Mechanism of Enhanced Susceptibility to Bacterial Pneumonia in Influenza-infected Hosts, Hazem Elsayed Ghoneim
NKG2D Ligands in Cancer, Neha Das Gupta
Developmental Characterization of the Choroid Plexus in Sialidosis (Neu1 Deficient) Mice, Danielle Lee Helton
Tetraspanin CD9: Contributions to Cancer Cell and Vascular Cell Phenotypes from the Sixth Man, Michael James Herr II
Determinants of Upper Genital Tract Complications in a Chlamydial Urogenital Mouse Model, Enitra N. Jones
In vitro and In vivo Characterization of the Infection Efficiency of a Modified Retrovirus Envelope Glycoprotein for Targeting Gene Transduction, Robin L. Krueger
Identification of Novel HIF1A Target Genes That Regulate Tumor Progression and Metastasis, Danielle L. Peacock
Full-Gestational Exposure to Nicotine and Ethanol Results in Long-Term Dysregulation in the Ventral Tegmental Area, Emily Elizabeth Roguski
Regulation of Secretory Phospholipase A2 by Thyroid Hormone, Pragya Sharma
Attenuation of Parenteral NutritionAssociated Liver Disease by Omega-3 Long-Chain Polyunsaturated Fatty Acids, Emma Monique Tillman
The Protumorigenic Role of Caspase-8 in Neuroblastoma, Devin Drew Twitchell
Signal Transduction and Transcriptional Regulation Pathways Essential for Azole Resistance in Candida albicans, Erin M. Vasicek
Theses/Dissertations from 2012
Acetaldehyde and Epithelial Junctions: Role of Pp2A and Occludin Phosphorylation, Mitzi Dunagan
CNS Penetration of Tyrosine Kinase Inhibitors in Mouse Models, Mohamed Elmeliegy
Neocortical Layer 4 to Layer 2/3 Sensory Information Processing Investigated with Digital-Light-Projection Neuronal Photostimulation, Jason Paul Jerome
Hematopoietic Stem Cell Threshold Sensing Controls Regulatory Pathways Facilitating Clinically Relevant Ex Vivo Expansion for Stem Cell Transplantation, Andrew D. Lasiter
Inhibition of Breast Cancer Angiogenesis and Metastasis ay Targeting Hypoxia-Inducible Factor-1α, Chikezie O. Madu
Mrp4 Is a Crucial Regulator of Testosterone Biosynthesis, Jessica Ann Morgan
Anti-apoptotic MCL-1 Localizes to the Mitochondrial Matrix and Couples Mitochondrial Fusion to Respiration, Rhonda Perciavalle
Contribution of the Unfolded Protein Response to VEGF Expression, Ethel Rose Pereira
The Role of the YXXΦ Motif in CD82 Trafficking and Function, Mekel Marie Richardson
Phenotypic And Electrophysiologic Characterization of a Mouse Model of Fragile X Syndrome, Snigdha Roy
The Role of BiP Nucleotide Exchange Factor Sil1 in Immunoglobulin Biosynthesis, Tyler Sanford
Discovery of Dihydroartemisinin and Dasatinib Drug Combination to Cure Pooroutcome BCR-ABL+ Acute Lymphoblastic Leukemia, Harpreet Singh
Metabotropic Glutamate Receptor 5 in the Medial Prefrontal Cortex: Role in Cocaine Sensitization and Addiction, Kristin Marie Timmer
Beta-2-Adrenergic Receptor Regulates Insulin Signaling to Reduce Cell Death in Müller Cells, Robert Jason Walker
Theses/Dissertations from 2011
The Biochemical Pathway Leading to Lpa Generation Upon Blood Coagulation, Alyssa Lynn Jefferson Bolen
Autoimmune Consequences of Histone Deimination during Neutrophil Activation, Nishant Dwivedi
Impact of Adjuvants on the Antibody Responses to Pre-pandemic H5N1 Influenza Vaccines, Ali Hassan Ellebedy
Insights into p53-Dependent Apoptotic Signaling and Cell Fate vis-a-vis Functional Cooperation among BCL-xL, Cytoplasmic p53, and PUMA, John C. Fisher
A Behavioral and Anatomical Analysis of Conditioned Taste Aversion in C57BL/6J and DBA/2J Mice, April Rebecca Glatt
The Treatment of Breast Cancer Tumor Growth and Metastasis With an Anti-MMP9 DNAzyme, Miranda A. Hallett
Role of Protein Kinase C Zeta (PKCζ) in Regulation of Epithelial Tight Junctions, Suneet Kumar Jain
Characterization of the Key Mouse Cochlear Developmental Genes for Auditory Hair Cell Regeneration, Zhiyong Liu
Testing Whether MRP4 (a cAMP Efflux Pump) and the Beta 2 Andrenergic Receptor (an Upstream Regulator of cAMP Signaling Pathways, Praveen Kumar Potukuchi
The Effects of PTEN Deletion on Cell Size and Plasticity in the Hippocampus, Margaret Sperow
Systemic AAV-Mediated Gene Therapy Using Epo-R76E to Protect Retinal Ganglion Cells from Optic Nerve Injury and Disease, Timothy A. Sullivan
Novel Insights into Ubiquitin-like Protein E1-E2 Interactions, Asad Taherbhoy
Characterization of the Mechanism of PPARγ-Mediated Neointima Formation in Rodents, Ryoko Tsukahara
Compound 49b: A Novel Beta-Adrenergic Receptor Agonist in the Treatment of Diabetic Retinopathy, Kimberly Williams-Guy
Pten Function in Postnatal Brain Development and Tumorigenesis, Guo Zhu