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Theses/Dissertations from 2019

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Regulation of CYP3A5 in Pancreatic Ductal Adenocarcinoma, Jessica D. Hoyer

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Study of Natural Killer Cells and Their Therapeutic Role in Pediatric Cancer, Hong Ha Rosa Nguyen

Theses/Dissertations from 2018

Molecular Interplay of Chromatin Remodeling Factor BRG1 and Transcription Factor STAT3 Regulates Stemness, Chemosensitivity and Tumorigenicity of Glioma Tumor Initiating Cells, Debolina Ganguly

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Understanding the Impact of BCRP and PGP Efflux Transporters on the Disposition of Their Endogenous, Xenobiotic and Dietary Substrates, Samit Ganguly

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Role of SMARCE1 and BHLHE40 in Breast Cancer Metastasis, Aarti Sethuraman

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Roles of Cytosolic Nucleic Acid Sensors in Cancer and Infection, Qifan Zhu

Theses/Dissertations from 2017

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Investigating the Role of Dispatched in Hedgehog Ligand Transport and Delivery, William Bodeen

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Metabolic Regulation of Cellular Signaling, Rashid John Darbandi

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Using S. pombe to Study the Biological Roles of the Histone Deacetylases Sir2 and Clr3 and the DEAD-Box RNA Helicase Ded1, Brandon Ray Lowe

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Revealing a Non-canonical Role of Anti-apoptotic MCL-1 in Early Embryonic Development, Xue Yang

Theses/Dissertations from 2016

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The Nucleolar Protein Nucleophosmin Undergoes Liquid-Liquid Phase Separation with Arginine-Rich Nucleolar Proteins through Weak, Multivalent Electrostatic Interactions, Jaclyn Alicia Cika

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Novel Oncogenic Drivers in Pediatric Gliomagenesis, Alexander K. Diaz

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The Roles of Nuclear Receptor NR4A1 in Cancer Cell Proliferation and Skeletal Muscle Differentiation, Alexa Farmer

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Environmental Signaling through the Target of Rapamycin Complex 1 (TORC1) and the Regulation of Epigenetic Mechanisms, Jason J. Workman

Theses/Dissertations from 2015

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Integration of ATM, ATR, and DNA-PKcs Signaling Maintains Genome Integrity During Neurogenesis, Vanessa D. Enriquez-Rios

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Reprogramming to Pluripotency Using Small Molecule Compounds, Brittany E. Greenberg

Theses/Dissertations from 2014

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Molecular Characterization of Glioblastoma Cancer Stem Cells, Jo Meagan Garner

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Functional and Genetic Analysis of Choroid Plexus Development in Zebrafish, Hannah Elizabeth Henson

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Characterization of Cre Mouse Models to Target CNS Barriers for Generating Conditional Knockouts of ABC Transporters, Rachel L. Scheib

Theses/Dissertations from 2013

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Development and Characterization of a Recombinant Vesicular Stomatitis Virus (rVSV) for the Treatment of Glioblastoma, Erika A. Dillard

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Functional Study of Hemogen Knockout Mouse Model, Peng Gao

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Identification of Novel HIF1A Target Genes That Regulate Tumor Progression and Metastasis, Danielle L. Peacock

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The Protumorigenic Role of Caspase-8 in Neuroblastoma, Devin Drew Twitchell

Theses/Dissertations from 2012

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Inhibition of Breast Cancer Angiogenesis and Metastasis ay Targeting Hypoxia-Inducible Factor-1α, Chikezie O. Madu

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Anti-apoptotic MCL-1 Localizes to the Mitochondrial Matrix and Couples Mitochondrial Fusion to Respiration, Rhonda Perciavalle

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Contribution of the Unfolded Protein Response to VEGF Expression, Ethel Rose Pereira

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The Role of the YXXΦ Motif in CD82 Trafficking and Function, Mekel Marie Richardson

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The Role of BiP Nucleotide Exchange Factor Sil1 in Immunoglobulin Biosynthesis, Tyler Sanford

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Discovery of Dihydroartemisinin and Dasatinib Drug Combination to Cure Pooroutcome BCR-ABL+ Acute Lymphoblastic Leukemia, Harpreet Singh

Theses/Dissertations from 2011

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Insights into p53-Dependent Apoptotic Signaling and Cell Fate vis-a-vis Functional Cooperation among BCL-xL, Cytoplasmic p53, and PUMA, John C. Fisher

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The Treatment of Breast Cancer Tumor Growth and Metastasis With an Anti-MMP9 DNAzyme, Miranda A. Hallett

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Characterization of the Key Mouse Cochlear Developmental Genes for Auditory Hair Cell Regeneration, Zhiyong Liu

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Pten Function in Postnatal Brain Development and Tumorigenesis, Guo Zhu

Theses/Dissertations from 2010

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The Use of Preclinical Models to Improve the Treatment of Retinoblastoma, Katie Marie Nemeth

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The Role of Pkd1 in Mouse Inner Ear Hair Cells, Katherine Ann Steigelman

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CD151 Reinforces Vascular Stability by Balancing Endothelial Cell Adhesion and Cytoskeletal Tension, Feng Zhang

Theses/Dissertations from 2009

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Pax5 Haploinsufficiency Cooperates with BCR-ABL1 to Induce Acute Lymphoblastic Leukemia, Christopher B. Miller